She loves to play 'real omamagoto', or 'real house', in which divorces and arguments are very common and she typically forces/blackmails the boys to play with her. She insists on being the mom all the time-and she forces her friends to do stuff they don't really want to do. This is always a nuisance to Shin-chan, Bo-chan, and Kazama-kun and a nightmare to Masao as he often needs to be Nene's husband (unsuccessful salaryman) in the plot. She occasionally sees her mother go crazy or do something out of character and shrieks something literally translated to be "You're not my usual mom!".
Nene styles herself as a sweet girl, but in fact she has inherited her mother's temper and is quite bossy. ike her mother, she hits a stuffed bunny to relieve her anger. Alternatively, Nene uses Masao as the lightning rod for her frustration when her bunny is not available. She considers Ai Suotome her rival and can't stand it when boys prefer Ai-chan to her. She has a sister named Nike Sakurada (Niku Chan). She has many pet cats whom she loves a lot, and she likes to see Magical Girl Moe-P. She is a member of the Kasukabe Defense Organization.
In the LUK Internacional dub she has a British accent.
English: Carrie Savage, Michelle Ruff, Anndi McAfee
Japanese: Tamao Hayashi
Italian: Francesca Manicone